| An in vivo MRI study of the changes in volume (and fluid content) of the lumbar intervertebral disc after overnight bed rest and during an 8-hour walking protocol. | |
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MedLine Citation:
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PMID: 11927827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Magnetic resonance imaging (MRI) was used to measure the changes in the volume (and fluid content) of the lumbar intervertebral discs (L1-L2, L2-L3, L3-L4, L4-L5) in five normal subjects. For each subject, MRI scans were taken at the end of a normal day and again on the following morning (after a night's bed rest). Ten further scans were taken during an 8-h protocol consisting of alternate periods of walking (40 min) and scanning (10 min). On average, 1) disc volume increased by 10.6% during overnight bed rest, which corresponds to a gain of about 0.9 cm(3) of fluid; 2) the rate of disc volume decrease during the 8-h walking protocol was 0.96 x 10(-3) cm(3)/min; and 3) after 8 h (using our walking/scanning protocol), the disc volume did not decrease to the volume measured at the end of the previous day. |
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Authors:
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John A Malko; William C Hutton; William A Fajman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of spinal disorders & techniques Volume: 15 ISSN: 1536-0652 ISO Abbreviation: J Spinal Disord Tech Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-04-02 Completed Date: 2002-06-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101140323 Medline TA: J Spinal Disord Tech Country: United States |
Other Details:
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Languages: eng Pagination: 157-63 Citation Subset: IM |
Affiliation:
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Department of Radiology, Emory University School of Medicine, Atlanta 30303, USA. jmalko@emory.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bed Rest* Extracellular Space / physiology* Female Fluid Shifts Humans Intervertebral Disk / anatomy & histology*, physiology* Lumbar Vertebrae* Magnetic Resonance Imaging* Male Walking* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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