| The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile. | |
| | |
MedLine Citation:
|
PMID: 2683699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To evaluate the determinants of left ventricular filling, left ventricular filling velocity was measured by pulsed Doppler flowmetry during catheterization of the right and left sides of the heart in 37 patients with cardiac disease before and during leg elevation. During leg elevation, despite no significant change in the time constant of isovolumic relaxation (T), the peak rapid filling velocity (PVRF) increased in association with an increase in pulmonary wedge pressure (PWP), but the peak atrial filling velocity was unchanged. The PVRF correlated with the pulmonary wedge V wave - left ventricular minimum pressure difference (r = 0.68) and in multivariate regression with both T and mean PWP (R = 0.73). These results indicate that left ventricular filling is determined by both left ventricular relaxation and left atrial pressure and that an increase in left atrial pressure changes the left ventricular filling velocity profile in a manner that mimics the pattern with normal diastolic function. |
| | |
Authors:
|
S Takagi; M Yokota; M Iwase; J Yoshida; H Hayashi; I Sotobata; M Koide; H Saito |
Related Documents
:
|
893679 - Evidence for cardiomyopathy in familial diabetes mellitus. 8221799 - Ventricular coupling via the pericardium: normal versus tamponade. 2963169 - Secondary hyperparathyroidism and cardiac hypertrophy in hemodialysis patients. 6618989 - Ventricular septal defects in the horse. 12131919 - Relationship between microalbuminuria and cardiac structural changes in mild hypertensi... 1389219 - Decreased and abnormal left ventricular filling in acute heart failure: role of pericar... 9300469 - Electrophysiological analysis of the response of males of the potato cyst nematode, glo... 7153119 - Breathing patterns influence aerosol deposition sites in excised dog lungs. 16670639 - The pressure-volume loop revisited: is the search for a cardiac contractility index a f... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American heart journal Volume: 118 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1989 Nov |
Date Detail:
|
Created Date: 1989-12-05 Completed Date: 1989-12-05 Revised Date: 2006-02-27 |
Medline Journal Info:
|
Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 954-62 Citation Subset: AIM; IM |
Affiliation:
|
First Department of Internal Medicine, Nagoya University School of Medicine, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Flow Velocity Blood Pressure* Coronary Circulation* Female Heart / physiopathology* Heart Atria Heart Diseases / physiopathology Heart Ventricles Humans Leg / physiology Male Middle Aged Mitral Valve / physiopathology Multivariate Analysis Myocardial Contraction* Posture Ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diabetic cardiomyopathy.
Next Document: Circadian patterns of myocardial ischemia.