Document Detail

The importance of second opinion in surgical pathology referral material of lymphoma.
MedLine Citation:
PMID:  22485235     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To evaluate the importance of inter-institutional second opinion surgical pathology review of lymphoma, and identify the lymphoma pathologic mimics.
METHODS: The surgical pathology material of patients referred to 2 tertiary care hospitals in the western region of Saudi Arabia (King Faisal Specialist Hospital and Research Centre and King Abdulaziz University Hospital, Jeddah, Saudi Arabia), for evaluation or therapy for lymphoma over a 10-year period (August 2001 to August 2011), were reviewed. This study included only cases in which the patient referred with a diagnosis previously made at the primary institution.
RESULTS: Of 560 cases, the second opinion diagnosis differed significantly from the initial diagnosis in 39 cases (7%). These include changing the diagnoses from lymphoma to non-lymphoma lesions, change the type of lymphoma with major clinical impact, and change from reactive/non-diagnostic to lymphoma.
CONCLUSION: Second opinion surgical pathology for lymphomas can result in major therapeutic and prognostic modifications. Thus, review of the original histologic material is recommended prior to a major therapeutic decision, and to maximize the discovery of clinically relevant major disagreements. Stringent adherence to institution's second opinion policy is an important quality assurance measure in surgical pathology.
Jaudah A Al-Maghrabi; Hassan H Sayadi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  33     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  399-405     Citation Subset:  IM    
Department of Pathology, Faculty of Medicine, King Abdulaziz University, PO Box 80205, Jeddah 21589, Kingdom of Saudi Arabia. Tel. +966 (2) 6401000 Ext 17069. Fax. +966 (2) 6408433. E-mail:
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