Document Detail


The importance of the ligation of the inferior thyroid artery in parathyroid function after subtotal thyroidectomy.
MedLine Citation:
PMID:  11082219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We prospectively studied the effects of the ligation of the inferior thyroid artery (ITA) on postoperative hypoparathyroidism in 48 patients who underwent functional subtotal thyroidectomy. Patients were randomized into two groups: A, with bilateral ligation of the ITA and B, without ligation of the ITA. Parathyroid function was checked preoperatively and after surgery by clinical examination and measurement of total calcium, intact PTH, urinary calcium, and AMPc. RESULTS: A significant incidence of postoperative hypocalcemia occurred: 17% in group A and 13% in B on the 4th postoperative day. Six months later, the incidence was 5% in Group A and 0% in Group B. These differences were not statistically significant between the two groups, and neither were any of the other clinical and laboratory observations. CONCLUSION: The ligation of the ITA was not an important causal factor for the occurrence of postoperative hypocalcemia after subtotal thyroidectomy.
Authors:
Araujo Filho VJ; Silva Filho GB; L G Brandão; L R Santos; A R Ferraz
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Revista do Hospital das Clínicas     Volume:  55     ISSN:  0041-8781     ISO Abbreviation:  Rev Hosp Clin Fac Med Sao Paulo     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2001-03-14     Completed Date:  2001-05-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0415246     Medline TA:  Rev Hosp Clin Fac Med Sao Paulo     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  113-20     Citation Subset:  IM    
Affiliation:
Department of Head and Neck Surgery, Hospital das Clinicas, Faculty of Medicine, University of Sao Paulo.
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MeSH Terms
Descriptor/Qualifier:
Adult
Arteries / surgery
Calcium / blood,  urine
Cyclic AMP / urine
Female
Graves Disease / surgery*
Humans
Hypocalcemia / etiology*
Ligation
Male
Parathyroid Glands / physiopathology*
Parathyroid Hormone / blood
Postoperative Period
Prospective Studies
Thyroid Gland / blood supply*
Thyroidectomy / adverse effects,  methods*
Chemical
Reg. No./Substance:
0/Parathyroid Hormone; 60-92-4/Cyclic AMP; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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