Document Detail

The importance of diastolic blood pressure in predicting cardiovascular risk.
MedLine Citation:
PMID:  20409835     Owner:  NLM     Status:  In-Data-Review    
Brachial systolic blood pressure (SBP) is the overall best predictor of future cardiovascular risk for the entire hypertensive population; however, there is much that can be learned from assessing diastolic blood pressure (DBP) in relation to simultaneous levels of SBP, because the former is not distorted by pressure amplification. Low DBP in very young adults (mean age 20 years), presenting as isolated systolic hypertension (ISH), results from elevation in stroke volume and/or arterial stiffness. This subtype of hypertension has a marked male predominance, occurs twice as frequently as essential hypertension, and is potentially not a benign condition. In contrast, isolated diastolic hypertension (IDH) in young adults (mean age of 40 years) with IDH occurs predominantly in men with a high prevalence of metabolic syndrome. Indeed, persons with IDH frequently evolve into systolic-diastolic hypertension and are potentially at increased risk for future diabetes and cardiovascular complications. The older age population with ISH and low DBP (mean age >/=60 years of age) has a high prevalence of left ventricular hypertrophy, increased ventricular-arterial stiffness, and a tendency for diastolic dysfunction and heart failure. Finally, concordant very high DBP, especially in older persons, defines potential hypertensive urgencies, emergencies, secondary forms of hypertension, and other high peripheral resistance states.
Stanley S Franklin
Related Documents :
11343005 - Effects of home telemonitoring and community-based monitoring on blood pressure control...
16368295 - The association between blood pressure and mortality in patients with heart failure.
11849415 - Pulse pressure and risk of total mortality and cardiovascular events in patients on chr...
19417635 - The 24-h blood pressure measurement may predict mortality and cardiovascular events in ...
7361285 - An analogue computer for pressure-time measurements in valvular heart disease.
6727725 - Comparison of in vitro valve pressure drop results from different investigators.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Society of Hypertension : JASH     Volume:  1     ISSN:  1933-1711     ISO Abbreviation:  J Am Soc Hypertens     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2010-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101312518     Medline TA:  J Am Soc Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  82-93     Citation Subset:  -    
Heart Disease Prevention Program, University of California, Irvine, California, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vascular inflammation.
Next Document:  Renalase is a novel renal hormone that regulates cardiovascular function.