| The importance of dedifferentiation in recurrent acinic cell carcinoma. | |
| | |
MedLine Citation:
|
PMID: 11535145 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The biological activity of acinic cell carcinoma is uncertain. Histological dedifferentiation is one possible reason for recurrent disease, and this study was undertaken to assess its importance in acinic cell carcinoma. The initial and recurrent specimens from five patients with acinic cell carcinoma were assessed histologically and using flow cytometry, AgNOR estimation and morphometric analysis for evidence of dedifferentiation. No objective evidence of a change in biological aggressiveness in recurrent acinic cell carcinoma was identified. In this limited series of a rare salivary gland tumour, it would appear that factors other than dedifferentiation, such as close/involved margins, histological type and stage have a more meaningful effect on the likelihood of recurrence and prognosis. |
| | |
Authors:
|
C I Timon; I Dardick |
Related Documents
:
|
15748305 - Complete response of metastatic renal cancer with dendritic cell vaccine. 17618455 - Basaloid adenocarcinoma. a new variant of pulmonary adenocarcinoma. 15502805 - Expression of aquaporins and pax-2 compared to cd10 and cytokeratin 7 in renal neoplasm... 2994505 - Primary combined small cell carcinoma of the larynx. 12880355 - Light scattering from normal and dysplastic cervical cells at different epithelial dept... 12918025 - Characterization of cellular carriers for use in injectable tissue-engineering composites. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of laryngology and otology Volume: 115 ISSN: 0022-2151 ISO Abbreviation: J Laryngol Otol Publication Date: 2001 Aug |
Date Detail:
|
Created Date: 2001-09-05 Completed Date: 2001-09-27 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8706896 Medline TA: J Laryngol Otol Country: England |
Other Details:
|
Languages: eng Pagination: 639-44 Citation Subset: AIM; IM |
Affiliation:
|
Department of Orolaryngology, Head and Neck Surgery, St James's Hospital, Dublin, Ireland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Carcinoma, Acinar Cell
/
genetics,
pathology* Coloring Agents Data Interpretation, Statistical Flow Cytometry Humans Mitotic Index Neoplasm Recurrence, Local / pathology* Nucleolus Organizer Region / ultrastructure Ploidies Prognosis Salivary Gland Neoplasms / genetics, pathology* Silver Staining |
| Chemical | |
Reg. No./Substance:
|
0/Coloring Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Increasing diagnostic yield in allergic fungal sinusitis.
Next Document: Reducing waiting times for sleep apnoea hypopnoea syndrome and snoring using a questionnaire and hom...