Document Detail

The implications of inflammation in odontogenic keratocysts.
MedLine Citation:
PMID:  3127567     Owner:  NLM     Status:  MEDLINE    
The histologic features of 112 odontogenic keratocysts (OKC's) were examined from both a clinical and histopathological perspective with emphasis on the microscopic presence of inflammation and its relationship to transformation of the classic epithelial cyst lining found in OKC's to a nonkeratinized lining characteristic of common inflammatory odontogenic cysts. Eighty-five (76%) of these cases exhibited inflammation. The sensitivity of inflammation as a predictor of this aforementioned transformation is 100%, and its positive predictive value is 88%. The specificity of the same parameters remains high at 73%. Using previous studies, the implications of these findings on the biologic behavior of OKC's is discussed with special reference to therapeutic considerations.
B Rodu; A L Tate; M G Martinez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral pathology     Volume:  16     ISSN:  0300-9777     ISO Abbreviation:  J. Oral Pathol.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-04-27     Completed Date:  1988-04-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0342050     Medline TA:  J Oral Pathol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  518-21     Citation Subset:  D; IM    
Department of Pathology, University of Alabama School of Medicine, Birmingham.
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MeSH Terms
Epithelium / pathology
Jaw Diseases / pathology*
Middle Aged
Odontogenic Cysts / pathology*

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