| An implantable Fabry-Pérot pressure sensor fabricated on left ventricular assist device for heart failure. | |
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MedLine Citation:
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PMID: 21997499 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Continuous flow left ventricular assist devices (LVADs) are commonly used as bridge-to-transplantation or destination therapy for heart failure patients. However, non-optimal pumping speeds can reduce the efficacy of circulatory support or cause dangerous ventricular arrhythmias. Optimal flow control for continuous flow LVADs has not been defined and calls for an implantable pressure sensor integrated with the LVAD for real-time feedback control of pump speed based on ventricular pressure. A MEMS pressure sensor prototype is designed, fabricated and seamlessly integrated with LVAD to enable real-time control, optimize its performance and reduce its risks. The pressure sensing mechanism is based on Fabry-Pérot interferometer principle. A biocompatible parylene diaphragm with a silicon mirror at the center is fabricated directly on the inlet shell of the LVAD to sense pressure changes. The sensitivity, range and response time of the pressure sensor are measured and validated to meet the requirements of LVAD pressure sensing. |
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Authors:
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Ming-Da Zhou; Chuan Yang; Zhiwen Liu; Joshua P Cysyk; Si-Yang Zheng |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-14 |
Journal Detail:
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Title: Biomedical microdevices Volume: - ISSN: 1572-8781 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100887374 Medline TA: Biomed Microdevices Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Bioengineering and Material Research Institute, Pennsylvania State University, University Park, PA, 16802, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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