| The impact of PET/CT on therapeutic strategy of patients with colorectal cancer metastasis. | |
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MedLine Citation:
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PMID: 19760922 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: The study's aim was to assess the impact of the PET/CT on the therapeutic strategy of the patients with colorectal cancer metastasis. METHODOLOGY: Fifteen patients who were suspicious of postoperative colorectal cancer metastasis were included in the study. Each patient received a positron emission tomography/computed tomography (PET/CT) after received contrast-enhanced computed tomography (ceCT). The therapeutic strategies were made before and after the PET/ CT respectively. The lesions confirmed by pathology or periodic follow up of ceCT (3 and 6 mo). RESULTS: Intrahepatic metastases were present in 5 of the 15 patients, total 9 lesions. The specificities of the PET/CT and ceCT were 100%. The patients with intrahepatic metastases were detected by PET/CT and ceCT with a sensitivity of 100% and 80%, respectively (p = 0.0009). Extrahepatic metastases were present in 11 of the 15 patients, total 32 lesions. The specificities of the PET/CT and ceCT were 75% and 50%, respectively. PET/ CT and ceCT were with a sensitivity of 100% and 63.6%, respectively (p = 0.0177). The therapeutic strategies were changed after received PET/CT in 6 (40%) of the 15 patients. CONCLUSIONS: PET/CT is superior to ceCT for the detection of the metastatic lesions of the colorectal cancer, and is a valuable tool to help select the correct therapeutic strategies. |
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Authors:
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Yan-Nan Liu; Mei-Xiong Huang; Qi An; Jun-Min Wei |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 56 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2009 Jul-Aug |
Date Detail:
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Created Date: 2009-09-17 Completed Date: 2009-10-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 968-70 Citation Subset: IM |
Affiliation:
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Department of General Surgery, Beijing Hospital, Beijing, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Colorectal Neoplasms / pathology, radiography*, radionuclide imaging* Contrast Media Female Humans Male Middle Aged Neoplasm Metastasis / pathology, radiography*, radionuclide imaging* Tomography, Emission-Computed / methods* Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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