| The impact of prophylactic treatment on post-traumatic epilepsy after severe traumatic brain injury. | |
| | |
MedLine Citation:
|
PMID: 17522989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIM: To assess the incidence of late post-traumatic epilepsy (PTE) in patients with very severe traumatic brain injury (TBI) who either received or did not receive anti-epileptic prophylactic treatment. METHODS: Two populations were studied: 55 patients retrospectively and 82 subjects prospectively. RESULTS: Ten patients (18%) in the first population showed late PTE. Although the incidence was lower in patients who did not receive prophylactic treatment, the difference between the treated and the non-treated group was not statistically significant. Sixty-nine patients in the second group (84%) had prophylactic treatment. Twenty-seven patients (39%) suffered from late PTE during the 2-year follow-up period and 17 of them (63%) showed EEG epileptic abnormalities. No patient who did not receive preventive therapy suffered from late PTE during the observation period. CONCLUSIONS: Due to the negative cognitive effects of anti-epileptic drugs, the preliminary results are of considerable interest for the rehabilitation of patients with very severe TBI. |
| | |
Authors:
|
R Formisano; C Barba; M G Buzzi; J Newcomb-Fernandez; F Menniti-Ippolito; R Zafonte; V Vinicola; F Spanedda |
Related Documents
:
|
3953319 - Primary hyperparathyroidism in patients with organic brain syndrome. 18633179 - Brain perfusion and cognitive function changes in hypertensive patients. 12136059 - Distinctly abnormal brain metabolism in late-onset ornithine transcarbamylase deficiency. 20624409 - The vertical-horizontal illusion in hemi-spatial neglect. 9660459 - Neurocysticercosis in ceará state, northeastern brazil: a review of 119 cases. 9874469 - A longitudinal magnetic resonance imaging study of the brain in survivors in childhood ... 2792029 - Can sharp waves localized at the sphenoidal electrode accurately identify a mesio-tempo... 7491699 - Microangiopathy following allogeneic marrow transplantation. association with cyclospor... 20950999 - Annular tilt as a screening test for right ventricular enlargement in patients with tet... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Brain injury : [BI] Volume: 21 ISSN: 0269-9052 ISO Abbreviation: Brain Inj Publication Date: 2007 May |
Date Detail:
|
Created Date: 2007-05-24 Completed Date: 2008-02-05 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8710358 Medline TA: Brain Inj Country: England |
Other Details:
|
Languages: eng Pagination: 499-504 Citation Subset: IM |
Affiliation:
|
Rehabilitation Hospital, I.R.C.C.S Santa Lucia Foundation, Rome, Italy. r.formisano@hsantalucia.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Anticonvulsants / administration & dosage, therapeutic use* Brain Injuries / complications*, drug therapy*, rehabilitation Cohort Studies Drug Administration Schedule Electroencephalography Epilepsy / diagnosis, epidemiology*, prevention & control* Female Humans Incidence Male Middle Aged Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Anticonvulsants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Methylphenidate effect on hemispheric attentional imbalance in patients with traumatic brain injury:...
Next Document: Overview and inter-rater reliability of an incident-based rating scale for aggressive behaviour foll...