Document Detail


The impact of pharmacogenetics in the treatment of allergic disease and asthma.
MedLine Citation:
PMID:  22073496     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Personalized medicine includes the application of genomic information in predicting disease and therapeutic response to ultimately individualize patient care. Pharmacogenetics is key in achieving true personalized care. However, the clinical applicability of genetic testing to "everyday medicine" is yet to be realized. This paper will discuss areas in allergic/inflammatory disease that have been impacted by pharmacogenetic research and how this application may be brought from the "bench to the bedside."
Authors:
Bridgette L Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Missouri medicine     Volume:  108     ISSN:  0026-6620     ISO Abbreviation:  Mo Med     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-11-11     Completed Date:  2011-12-13     Revised Date:  2013-05-24    
Medline Journal Info:
Nlm Unique ID:  0400744     Medline TA:  Mo Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  361-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Children's Mercy Hospital and Clinics, USA. bljones@cmh.edu
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MeSH Terms
Descriptor/Qualifier:
Administration, Inhalation
Adrenal Cortex Hormones / therapeutic use
Anti-HIV Agents / immunology,  therapeutic use
Asthma / genetics*,  therapy*
Bronchodilator Agents / therapeutic use
Dideoxynucleosides / immunology,  therapeutic use
Genetic Association Studies
Humans
Hypersensitivity / therapy*
Pharmacogenetics
Polymorphism, Single Nucleotide
Trimethoprim-Sulfamethoxazole Combination / therapeutic use
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-HIV Agents; 0/Bronchodilator Agents; 0/Dideoxynucleosides; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination; WR2TIP26VS/abacavir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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