Document Detail

The impact of performance uncertainty on the postimperative negative variation.
MedLine Citation:
PMID:  8753943     Owner:  NLM     Status:  MEDLINE    
In a delayed matching-to-sample task, the impact of clear or ambiguous go versus clear no-go signals on the post-imperative negative variation (PINV) was examined in 11 patients with a chronic schizophrenic disorder (DSM-III-R) and in a control group of 13 healthy subjects matched to the patient sample by age, sex, and education. Size and spatial position of a visual S2 had to be matched to one of two visual patterns in the S1 presented 4 s earlier. In 96 trials, the S2 was identical in size with one of the two patterns of S1 (clear matching). These trials varied pseudorandomly, with 60 trials in which the S2 was of intermediate size. On a randomly interspersed additional 48 trials, an S2 differing in color and shape signaled no-go. The electroencephalogram was recorded from Fz, Cz, Pz, F3, F4, C3, C4, P3, and P4. Although groups did not differ in contingent negative variation amplitude, the PINV was generally more pronounced in patients than in controls. In both groups, ambiguity of the to-be-matched S2 produced larger PINV amplitudes; the no-go signal elicited only a small PINV. Differential effects of ambiguity and no-go on PINV amplitude and its scalp distribution suggest that "performance" and "action" uncertainty contribute to PINV generation and that thresholds for both effects are reduced in schizophrenics.
C Klein; B Rockstroh; R Cohen; P Berg; M Dressel
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Psychophysiology     Volume:  33     ISSN:  0048-5772     ISO Abbreviation:  Psychophysiology     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-10-04     Completed Date:  1996-10-04     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0142657     Medline TA:  Psychophysiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  426-33     Citation Subset:  IM    
Department of Psychology, University of Konstanz, Germany.
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MeSH Terms
Acoustic Stimulation
Contingent Negative Variation / physiology*
Evoked Potentials / physiology
Psychomotor Performance / physiology*
Schizophrenic Psychology

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