Document Detail

The impact of noninvasive ventilation during the physical training in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).
MedLine Citation:
PMID:  17505694     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the influence of physical training with or without noninvasive ventilation at 2 levels of pressure in the airways (BiPAP) in patients with chronic obstructive pulmonary disease. METHODS: Eighteen patients with FEV(1) = 34 +/- 8% of predicted values, mean age of 68 +/- 9 years were randomly distributed into 2 groups, one group performing physical training on a treadmill and the other group performing physical training associated with BiPAP (physical training+B), for 30 minutes, 3 times a week for 12 weeks. The training velocity was based on a test of cardiopulmonary force performed pre- and postintervention, which registered the values for heart rate, systolic blood pressure, diastolic blood pressure, peripheral oxygen saturation, blood lactate, sensation of dyspnea, respiratory muscle strength, and analysis of gases expired such as oxygen consumption and the production of carbon dioxide. RESULTS: For both groups, there was a significant improvement in dyspnea and peripheral oxygen saturation at identical levels of physical exercise, in distance walked during the physical training, and in respiratory muscle strength (P < 0.05). Only the physical training+B group had a significant improvement in heart rate, systolic blood pressure, and oxygen consumption after training (P < 0.05). Significant reductions of blood lactate were observed at identical levels of exercise in physical training+B when compared to isolated physical training (from 1.3 +/- 0.7 mMol/L versus 2.5 +/- 0.9 mMol/L, (P < 0.05), respectively). CONCLUSION: Physical training associated with BiPAP enhanced the oxidative muscular capacity and could be an adjunctive recourse for physical rehabilitation in patients with chronic obstructive pulmonary disease.
Andreza Toledo; Audrey Borghi-Silva; Luciana Maria Malosá Sampaio; Karla Paiva Ribeiro; Vilmar Baldissera; Dirceu Costa
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinics (São Paulo, Brazil)     Volume:  62     ISSN:  1807-5932     ISO Abbreviation:  Clinics (Sao Paulo)     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-05-16     Completed Date:  2008-07-29     Revised Date:  2009-05-20    
Medline Journal Info:
Nlm Unique ID:  101244734     Medline TA:  Clinics (Sao Paulo)     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  113-20     Citation Subset:  IM    
Federal University of São Carlos, São Carlos, SP, Brazil.
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MeSH Terms
Exercise Test
Exercise Therapy*
Oxygen Consumption / physiology
Pulmonary Disease, Chronic Obstructive / rehabilitation*
Pulmonary Gas Exchange / physiology
Respiration, Artificial*
Respiratory Physiological Phenomena
Severity of Illness Index
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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