| The impact of maternal ketonuria on fetal test results in the setting of postterm pregnancy. | |
| | |
MedLine Citation:
|
PMID: 11262477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The aim of this study was to determine whether ketonuria, a commonly assessed urinary marker of maternal starvation and dehydration, is associated with abnormal fetal test results in the setting of postterm pregnancy. STUDY DESIGN: During a 4-year period (January 1993-December 1996), a total of 3655 visits for antepartum maternal-fetal testing of postterm pregnancies (> or =41 weeks' gestation) occurred at our institution. Maternal assessment included vital signs and urinalysis. The presence and degree of maternal ketonuria was correlated against abnormal results of fetal heart rate tests, nonstress tests, amniotic fluid index measurements, and biophysical profile scores performed on the same day. RESULTS: There were 3601 encounters suitable for inclusion in the study. Clinically detectable ketonuria occurred in 10.9% of the patients studied. Patients with clinically detectable ketonuria were at increased risk relative to patients without ketonuria for abnormal outcomes during postterm testing, including the presence of oligohydramnios (24% vs. 9.3%; P<.0001 ), nonreactive nonstress tests (6.2% vs. 2.15%; P<.0001), and fetal heart rate decelerations (14% vs 9.2%; P =.0039 ). CONCLUSION: Maternal ketonuria among patients with postterm pregnancy was associated with a >2-fold increase in the occurrence of oligohydramnios, a 3-fold increase in nonreactive nonstress tests, and a significant increase in fetal heart rate decelerations. Further studies are required to evaluate the potential benefits of treating ketonuria before fetal testing. |
| | |
Authors:
|
C I Onyeije; M Y Divon |
Related Documents
:
|
623167 - The effects of paracervical block on uterine activity and beat-to-beat variability of t... 12039107 - Characteristics of maternal heart rate patterns during labor and delivery. 9764667 - Magnesium sulfate, maternal hypothermia, and fetal bradycardia with loss of heart rate ... 9125247 - Cardiac expression of 52beta, an alternative transcript of the congenital heart block-a... 9175687 - Anti-beta 2 glycoprotein i antibodies in a general obstetric population: preliminary re... 21413857 - The impact of hyperemesis gravidarum on maternal mental health and maternal-fetal attac... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 184 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2001 Mar |
Date Detail:
|
Created Date: 2001-03-23 Completed Date: 2001-04-26 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 713-8 Citation Subset: AIM; IM |
Affiliation:
|
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology and Women's Health, Lenox Hill Hospital, Albert Einstein College of Medicine, NY 10021, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Amniotic Fluid Analysis of Variance Body Weight Dehydration / complications Female Gestational Age Heart Rate, Fetal* Humans Ketone Bodies / urine* Linear Models Oligohydramnios / etiology* Parity Pregnancy Pregnancy, Prolonged / urine* Specific Gravity Urinalysis |
| Chemical | |
Reg. No./Substance:
|
0/Ketone Bodies |
| Comments/Corrections | |
Comment In:
|
Am J Obstet Gynecol. 2002 Nov;187(5):1425; author reply 1425
[PMID:
12439543
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Developmental changes in reactivity of small femoral arteries in the fetal and postnatal baboon.
Next Document: Fetal loss rate associated with cordocentesis at midgestation.