| The impact of intra-aortic balloon pumping on cardiac output determination by pulmonary arterial and transpulmonary thermodilution in pigs. | |
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MedLine Citation:
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PMID: 16750730 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to evaluate the impact of intra-aortic balloon pumping (IABP) on the comparison of simultaneous measurements of cardiac output via pulmonary arterial and transpulmonary thermodilution (PiCCO; Pulsion Medical Systems, Munich, Germany). DESIGN: Prospective. SETTINGS: University research laboratory. PARTICIPANTS: The data were derived from 9 anesthetized (fentanyl, propofol, flunitrazepam, rocuronium) and ventilated pigs. INTERVENTIONS: A thermodilution catheter was inserted into the pulmonary artery, a PiCCO catheter into the abdominal aorta through the right femoral artery, epicardial atrial pacing wires through a thoracotomy, and a balloon catheter for counterpulsation into the descending thoracic aorta through the left femoral artery. Cardiac output was varied over a wide range by cardiac pacing between 80 and 150/min in steps of 10/min and was measured without and during IABP at an assist frequency of 1:1. MEASUREMENTS AND MAIN RESULTS: A total of 236 paired cardiac output measurements were carried out in a range of cardiac output between 1.4 to 4.9 L/min. A close correlation was found between transpulmonary and pulmonary arterial thermodilution both without and during IABP (r = 0.94 and 0.93, respectively) and a good agreement of both methods (bias of 0.30 and 0.26 L/min, respectively; precision 0.47 and 0.52 L/min, respectively). CONCLUSIONS: Transpulmonary thermodilution is suitable for cardiac output measurement during IABP. Hence, in critically ill patients with cardiac pump failure, blood flow may be determined as accurately with the less-invasive transpulmonary method as with the traditional pulmonary arterial thermodilution one. |
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Authors:
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Matthias Janda; Thomas W L Scheeren; Jörn Bajorat; Bernd Westphal; Dierk A Vagts; Birgit Pohl; Corneliu Popescu; Rainer Hofmockel |
Publication Detail:
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Type: Journal Article Date: 2006-03-27 |
Journal Detail:
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Title: Journal of cardiothoracic and vascular anesthesia Volume: 20 ISSN: 1053-0770 ISO Abbreviation: J. Cardiothorac. Vasc. Anesth. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-06-05 Completed Date: 2006-10-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9110208 Medline TA: J Cardiothorac Vasc Anesth Country: United States |
Other Details:
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Languages: eng Pagination: 320-4 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology and Intensive Care Medicine, University of Rostock, Rostock, Germany. matthias.janda@medizin.uni-rostock.de |
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cardiac Output* Female Intra-Aortic Balloon Pumping* Male Prospective Studies Pulmonary Artery / physiology* Swine Thermodilution* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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