Document Detail

The impact of genetic markers on the diagnosis of lung cancer: a current perspective.
MedLine Citation:
PMID:  17975498     Owner:  NLM     Status:  MEDLINE    
Lung cancer is the leading worldwide source of cancer-related death. It is acknowledged that prognosis and treatment outcomes in lung cancer might be improved by increasing the effectiveness of early-stage diagnosis. Several recently published studies have produced intriguing results regarding the detection of biomarkers in tumor samples, but also in easily accessible specimens such as sputum, plasma, and exhaled breath condensate. This review presents advances in genetic diagnostics of lung cancer, with particular reference to the clinical usefulness of individual biomarkers, specimens, and methods. The adequacy of their sensitivity and specificity for cancer screening and early detection is discussed in detail.
Joanna Chorostowska-Wynimko; Adam Szpechcinski
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer     Volume:  2     ISSN:  1556-1380     ISO Abbreviation:  J Thorac Oncol     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-02     Completed Date:  2008-01-10     Revised Date:  2008-05-06    
Medline Journal Info:
Nlm Unique ID:  101274235     Medline TA:  J Thorac Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1044-51     Citation Subset:  IM    
Laboratory of Molecular Diagnostics, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.
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MeSH Terms
Genetic Markers / genetics
Lung Neoplasms / diagnosis*,  genetics,  metabolism
Molecular Diagnostic Techniques
Tumor Markers, Biological / genetics*
Reg. No./Substance:
0/Genetic Markers; 0/Tumor Markers, Biological

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