| The impact of gender on vessel size in patients with angiographically normal coronary arteries. | |
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MedLine Citation:
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PMID: 16881982 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Female gender has been associated with worse clinical outcomes following coronary revascularization. Whether a gender-specific difference in vessel size is contributing to this finding remains controversial. We sought to better define the relationship between gender and coronary artery size. METHODS: Baseline characteristics were obtained and quantitative coronary angiography was performed on 145 consecutive patients with angiographically normal (smooth luminal surface with no evidence of any irregularity in the coronary tree) coronary arteries. Two separate orthogonal measurements each were taken of the left main, proximal left anterior descending, proximal circumflex, proximal right coronary artery, and ostial posterior descending arteries. An average coronary size, derived from five separate coronary artery measurements, was tabulated for each patient. RESULTS: After correcting for confounding variables, including BSA, height, diabetes, and left ventricular hypertrophy using multivariate linear regression, female gender remained a strong independent predictor of coronary vessel size (Beta =-0.30, P = 0.004). Female gender was associated with a 0.30 mm decrease in average coronary size. CONCLUSION: Gender is a strong, independent predictor of coronary artery size even when taking into account differences in body size. This difference may contribute to worse outcomes of women undergoing coronary revascularization. |
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Authors:
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Felix Yang; Robert M Minutello; Sherrita Bhagan; Atul Sharma; S Chiu Wong |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of interventional cardiology Volume: 19 ISSN: 0896-4327 ISO Abbreviation: J Interv Cardiol Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-08-02 Completed Date: 2006-10-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8907826 Medline TA: J Interv Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 340-4 Citation Subset: IM |
Affiliation:
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Department of Medicine, Weill Cornell Medical College, New York, New York 10021, USA. fey2002@med.cornell.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Chest Pain / epidemiology, radiography Confounding Factors (Epidemiology) Coronary Angiography* Coronary Artery Disease / epidemiology, pathology, radiography Coronary Vessels / anatomy & histology* Female Humans Linear Models Male Middle Aged Predictive Value of Tests Sex Characteristics* Sex Distribution Sex Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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