| The impact of exercise duration and intensity on the release of cardiac biomarkers. | |
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MedLine Citation:
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PMID: 19919634 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Numerous studies have observed cardiac biomarker release with prolonged exercise. Despite this, we are unsure as to the constituent aspects of any given exercise bout that may be important in promoting cardiac biomarker release. This study examined the influence of exercise duration and intensity on the appearance of cardiac biomarkers. Twenty-one subjects ran for 45, 90 and 180 min at 85% and 95% of their individual anaerobic threshold on six different days randomized. Cardiac troponin I (cTnI) and N-terminal pro-brain natiuretic peptide (NT-proBNP) were assayed from blood samples collected before, 30 min and 3 h post-exercise. NT-proBNP was elevated after all exercise trials (range before: 21-32; range post: 38-67 ng/L). Peak post-exercise concentrations of NT-proBNP were associated with exercise duration (P=0.049), but not exercise intensity (P=0.451). cTnI was elevated after all exercise trials (range before: 0.007-0.011; range post: 0.008-0.021 μg/L). Peak post-exercise concentrations of cTnI were associated with exercise duration (P=0.003) and intensity (P=0.037). Data suggest that while both cTnI and NT-proBNP increased after all exercise trials, the mediating effect of duration influenced both NT-proBNP and cTnI while intensity influenced only cTnI. |
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Authors:
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E Serrano-Ostáriz; J L Terreros-Blanco; A Legaz-Arrese; K George; R Shave; P Bocos-Terraz; S Izquierdo-Álvarez; J L Bancalero; J M Echavarri; J Quilez; M T Aragonés; L E Carranza-García |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of medicine & science in sports Volume: 21 ISSN: 1600-0838 ISO Abbreviation: Scand J Med Sci Sports Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9111504 Medline TA: Scand J Med Sci Sports Country: Denmark |
Other Details:
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Languages: eng Pagination: 244-9 Citation Subset: IM |
Copyright Information:
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© 2009 John Wiley & Sons A/S. |
Affiliation:
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Section of Physical Education and Sports, University of Zaragoza, Zaragoza, Spain Sports Medicine Center, Aragón Government, Zaragoza, Spain Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, UK Service of Biochemistry, Miguel Servet University Hospital, Zaragoza, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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