Document Detail


The impact of endurance exercise training on left ventricular torsion.
MedLine Citation:
PMID:  20947045     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: We sought to examine the effect of endurance exercise training (EET) on peak systolic left ventricular torsion (LVT) and peak early diastolic untwisting rate (UTR).
BACKGROUND: Left ventricular (LV) structural adaptations to EET have been well characterized. LVT, a recognized marker of LV function in numerous cardiac diseases, has recently been investigated in the setting of exercise. However, longitudinal data characterizing the impact of sustained exercise training on LVT have not been reported.
METHODS: A prospective, longitudinal study design examined the impact of a 90-day period of training on LV twist mechanics in university male rowers (n = 15, mean age 18.6 ± 0.5 years). Conventional LV structural measurements, LV apical and basal rotation, peak systolic LVT, and peak early diastolic UTR were measured by 2-dimensional and speckle tracking echocardiography before and after the EET study period.
RESULTS: Participants experienced LV eccentric hypertrophy, characterized by increased LV end-diastolic volume (80.8 ± 8.7 ml/m(2) vs. 91.3 ± 8.0 ml/m(2), p < 0.001) and LV mass (101.3 ± 11.4 g/m(2) vs. 115.7 ± 12.6 g/m(2), p = 0.001). There was a significant increase in peak systolic apical rotation (8.9 ± 4.2° vs. 12.7 ± 3.9°, p = 0.002) but no change in basal rotation. This translated into a highly significant increase in peak systolic LVT after EET (14.1 ± 5.0° vs. 18.0 ± 3.6°, p = 0.002). The impact of EET on LV twist mechanics was not confined to ventricular systole, as peak early diastolic UTR (-110.6 ± 41.8°/s vs. -148.0 ± 29.8°/s, p = 0.003) and the percentage of untwisting that occurred by the end of isovolumic relaxation (31.2 ± 12.0% vs. 39.9 ± 14.9%, p = 0.04) increased.
CONCLUSIONS: Participation in EET was associated with significant changes in LV twist mechanics characterized by increased apical rotation, LVT, and UTR. These findings suggest that LVT and UTR augmentation may be an important and previously unrecognized component of exercise-induced cardiac remodeling.
Authors:
Rory B Weiner; Adolph M Hutter; Francis Wang; Jonathan Kim; Arthur E Weyman; Malissa J Wood; Michael H Picard; Aaron L Baggish
Related Documents :
22375205 - The effects of aerobic versus resistance training on cardiovascular fitness in obese se...
6645045 - Left ventricular size and performance during graded supine exercise in normal subjects.
18621855 - The impact of endurance exercise training on left ventricular systolic mechanics.
6638925 - Functional limitation in aortic valve disease: superiority of bicycle test to symptom-r...
24829145 - The association between exercise behavior regulation and exergaming in adolescents.
19127215 - Brief bout of exercise alters gene expression in peripheral blood mononuclear cells of ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JACC. Cardiovascular imaging     Volume:  3     ISSN:  1876-7591     ISO Abbreviation:  JACC Cardiovasc Imaging     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-15     Completed Date:  2011-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101467978     Medline TA:  JACC Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1001-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Affiliation:
Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. rweiner@partners.org
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Adolescent
Biomechanics
Echocardiography, Doppler, Color
Echocardiography, Doppler, Pulsed
Heart Ventricles / ultrasonography
Humans
Hypertrophy, Left Ventricular / physiopathology,  ultrasonography
Longitudinal Studies
Male
Physical Endurance*
Prospective Studies
Resistance Training
Time Factors
Torsion, Mechanical
Ventricular Function, Left*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Natural history of left ventricular mechanics in transplanted hearts: relationships with clinical va...
Next Document:  Comparison of the extent and severity of myocardial perfusion defects measured by CT coronary angiog...