Document Detail

The impact of diagnostic immunohistochemistry on patient outcomes.
MedLine Citation:
PMID:  10572716     Owner:  NLM     Status:  MEDLINE    
Diagnostic immunohistology (DIHC) is a discipline that has been used clinically for at least two decades, but, because of medicolegal encumbrances, it has not been a part of many formal outcomes analyses during that time. Potential applications of this technology with a direct bearing on response to treatment include the accurate identification of infectious organisms, distinction between morphologically-similar undifferentiated tumors, separation of benign and malignant neoplasms, and prognostication of malignancies. The first two of those four roles may indeed have a quantifiable impact on case outcomes, but the last two applications have only questionable value in this specific context. This is an area of medicine in which formal outcomes analysis is greatly needed to help determine future practice patterns.
M R Wick; J H Ritter; P E Swanson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in laboratory medicine     Volume:  19     ISSN:  0272-2712     ISO Abbreviation:  Clin. Lab. Med.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  1999-12-09     Completed Date:  1999-12-09     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8100174     Medline TA:  Clin Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  797-814, vi     Citation Subset:  IM    
Robert E. Fechner Laboratory of Surgical Pathology, University of Virginia Medical Center, Charlottesville, USA.
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MeSH Terms
Cost-Benefit Analysis
Immunohistochemistry / economics,  standards*
Neoplasms / diagnosis*
Outcome Assessment (Health Care)*
Pathology, Clinical / economics,  standards*
Reproducibility of Results

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