Document Detail

The impact of chronic smoking on rectal mucosal blood flow.
MedLine Citation:
PMID:  19730785     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Chronic smoking adversely affects peripheral vasculature. The aim of the present study was to investigate the effect of chronic cigarette smoking on rectal microvascular blood flow. METHODS: Rectal mucosal blood flow (MBF) was measured in 80 subjects (44 smokers and 36 non-smokers). The MBF was measured in the four quadrants of the rectum by laser Doppler flowmetry. RESULTS: Rectal perfusion was found to be significantly lower in posterior midline compared to the other sites. In chronic smokers the observed MBF measured at the posterior and ventral sites was significantly lower compared to non-smokers (P = 0.04 and P = 0.03, respectively). CONCLUSIONS: Our results suggest that rectal mucosal blood flow is reduced in chronic smokers.
A F J De Bruin; S B Schouten; P P S de Kort; M P Gosselink; E van der Harst
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Techniques in coloproctology     Volume:  13     ISSN:  1128-045X     ISO Abbreviation:  Tech Coloproctol     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-01-26     Completed Date:  2010-04-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9613614     Medline TA:  Tech Coloproctol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  269-72     Citation Subset:  IM    
Division of Colon and Rectal surgery, Department of Surgery, Maasstad Ziekenhuis, Brede Hilledijk 315, 3075 EA Rotterdam, The Netherlands.
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MeSH Terms
Intestinal Mucosa / blood supply*
Laser-Doppler Flowmetry
Middle Aged
Rectum / blood supply*
Regional Blood Flow
Smoking / physiopathology*

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