Document Detail

The impact of birth weight on coronary heart disease morbidity and mortality in a birth cohort followed up for 85 years: a population-based study of men born in 1913.
MedLine Citation:
PMID:  15554948     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To analyse whether there is a relationship between birth weight on the one hand and coronary heart disease (CHD) and cardiovascular disease (CVD) mortality and morbidity on the other, whether such a relationship is influenced by potential modifying factors from the time of birth, adult height and the presence of diabetes, and what significance these possible associations might have for the CHD and CVD rates in the general population. DESIGN: Population-based birth cohort. SETTING: Sweden. SUBJECTS: A total of 1319 singleton men born in 1913, surviving until age 20 and from then on followed until 85 years of age. MAIN OUTCOME MEASURES: CHD and CVD mortality and morbidity events. RESULTS: The gestational age adjusted CHD and CVD mortality and morbidity hazard ratios were virtually unaffected by birth weight. Taking possible effect-modifying variables into account did not change the results. The population attributable risk percentage for CHD and CVD mortality and morbidity due to a birth weight <or=3000 g was 1% or less. CONCLUSIONS: Birth weight did not significantly affect CHD or CVD mortality or morbidity. A birth weight <or=3000 g contributes little to the burden of CHD and CVD on a community level.
M Eriksson; M-A Wallander; I Krakau; H Wedel; K Svärdsudd
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of internal medicine     Volume:  256     ISSN:  0954-6820     ISO Abbreviation:  J. Intern. Med.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-11-23     Completed Date:  2004-12-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904841     Medline TA:  J Intern Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  472-81     Citation Subset:  IM    
Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology Section, Uppsala University, S-751 85 Uppsala, Sweden.
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MeSH Terms
Aged, 80 and over
Birth Weight*
Body Height
Cardiovascular Diseases / epidemiology,  etiology
Cohort Studies
Coronary Disease / epidemiology*,  etiology,  mortality
Diabetic Angiopathies / epidemiology
Gestational Age
Middle Aged
Risk Factors
Social Class
Sweden / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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