Document Detail

The impact of allergy on atopic eczema from data from epidemiological studies.
MedLine Citation:
PMID:  18769194     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: We aimed to review the association between atopic eczema and allergic sensitization and food allergy and its determinants on the basis of current epidemiological literature. RECENT FINDINGS: About 50% of children with atopic eczema and about 35% of adults are sensitized to common allergens. Gender, geography (e.g. East and West Germany), and socioeconomic factors determine the proportion of atopic eczema with allergic sensitization. Allergic sensitization in addition to atopic eczema obviously increases the risk for respiratory allergies. Sensitization to house dust mites seems to be important and clinically relevant for atopic eczema. Population-based studies on the association between food allergy and atopic eczema are limited. Although, up to 40% of children in hospital settings react to certain food allergens by a flare-up of their atopic eczema, there is an indication that on a population basis, adults with atopic eczema do only react occasionally with a worsening of their skin disease due to food allergens. SUMMARY: Atopic eczema is not necessarily associated with allergic sensitization. Sensitization to house dust mites, however, seems to be clinically relevant. The impact of food allergy on atopic eczema is difficult to assess on the basis of epidemiological studies and more detailed studies are needed.
Torsten Schäfer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in allergy and clinical immunology     Volume:  8     ISSN:  1473-6322     ISO Abbreviation:  Curr Opin Allergy Clin Immunol     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-04     Completed Date:  2008-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100936359     Medline TA:  Curr Opin Allergy Clin Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  418-22     Citation Subset:  IM    
Institute of Social Medicine, Lübeck University, Lübeck, Germany.
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MeSH Terms
Allergens / immunology*
Child, Preschool
Dermatitis, Atopic / diagnosis,  epidemiology*,  etiology,  immunology
Dust / immunology
Food Hypersensitivity / complications*,  epidemiology*,  immunology
Mites / immunology
Respiratory Hypersensitivity / complications*,  epidemiology*,  immunology
Reg. No./Substance:
0/Allergens; 0/Dust

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