| The impact of 18-fluorodeoxyglucose positron emission tomography-computed tomography on the staging and management of primary rectal cancer. | |
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MedLine Citation:
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PMID: 18461399 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: 18-Fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) has a role in recurrent colorectal cancer. This study was designed to assess the impact of PET-CT on management of primary rectal cancer. METHODS: Eighty-three patients with rectal cancer underwent PET-CT scan between 2002 and 2005. Referring physicians prospectively recorded stage and management plan after conventional imaging before PET-CT scan, which were compared to subsequent stage and management after PET-CT. RESULTS: Staging PET-CT caused a change in stage from conventional imaging in 26 patients (31 percent). Twelve (14 percent) were upstaged (7 change in N stage; 4 change in M stage; 1 change in N and M stage), and 14 (17 percent) were downstaged (10 change in N stage; 3 change in M stage; 1 change in N and M stage). PET-CT scan altered management intent in seven patients (8 percent) (curative to palliative 6 patients; palliative to curative 1 patient). Management was altered in ten patients (12 percent). There was no difference in impact with respect to tumor height. CONCLUSIONS: PET-CT scan impacts the management of patients with primary rectal cancer and influences staging/therapy in a third of patients and should be a component of rectal cancer workup. |
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Authors:
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K Davey; A G Heriot; J Mackay; E Drummond; A Hogg; S Ngan; A D Milner; R J Hicks |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-05-07 |
Journal Detail:
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Title: Diseases of the colon and rectum Volume: 51 ISSN: 1530-0358 ISO Abbreviation: Dis. Colon Rectum Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-07-03 Completed Date: 2008-07-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372764 Medline TA: Dis Colon Rectum Country: United States |
Other Details:
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Languages: eng Pagination: 997-1003 Citation Subset: IM |
Affiliation:
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Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology,
radionuclide imaging*,
therapy* Adult Aged Aged, 80 and over Biopsy Combined Modality Therapy / methods Female Fluorodeoxyglucose F18 / diagnostic use* Follow-Up Studies Humans Magnetic Resonance Imaging Male Middle Aged Neoplasm Staging / methods Positron-Emission Tomography / methods* Prognosis Prospective Studies Radiopharmaceuticals / diagnostic use* Rectal Neoplasms / pathology, radionuclide imaging*, therapy* Reproducibility of Results |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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