Document Detail

The immunological approach to pregnancy diagnosis: a review.
MedLine Citation:
PMID:  6966439     Owner:  NLM     Status:  MEDLINE    
The developing embryo/fetus bears antigens which are foreign to the mother and it could be expected that immune rejection of the conceptus would occur. One of the reasons why the fetus is not rejected is because a depression of the maternal immune response takes place during pregnancy. Serum from pregnant animals of several species has been shown to contain a factor, early pregnancy factor (EPF), which is immunosuppressive. EPF has been detected as early as six hours after mating and its detection could aid diagnosis of early pregnancy in all species.
F D Shaw; H Morton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  106     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1980 Mar 
Date Detail:
Created Date:  1980-07-26     Completed Date:  1980-07-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  268-70     Citation Subset:  IM    
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MeSH Terms
Chaperonin 10
Fetus / immunology
Horses / immunology,  physiology
Immune Tolerance
Immunosuppressive Agents / blood
Pregnancy Proteins*
Pregnancy Tests, Immunologic / veterinary*
Rosette Formation
Sheep / immunology,  physiology
Suppressor Factors, Immunologic*
T-Lymphocytes / immunology
Reg. No./Substance:
0/Chaperonin 10; 0/Immunosuppressive Agents; 0/Peptides; 0/Pregnancy Proteins; 0/Suppressor Factors, Immunologic; 0/early pregnancy factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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