Document Detail

An immunocytochemical study of the carbonic anhydrase I isoenzyme in human oral Merkel cells.
MedLine Citation:
PMID:  9022928     Owner:  NLM     Status:  MEDLINE    
Merkel cells in human buccal mucosa and hard palate possess the carbonic anhydrase I isoenzyme (CAI). CAI colocalized immunocytochemically with a range of Merkel cell cytokeratins, namely CK 7, 8, 18, 19 and 20. No other cells in the oral epithelium were immunoreactive for the CAI antibody. The presence of the enzyme may be related to the function of sensory receptors that produce a sustained response to a maintained mechanical stimulus.
K N Christie; C Thomson; D Hopwood; A A Harper; G R Ogden
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of oral biology     Volume:  41     ISSN:  0003-9969     ISO Abbreviation:  Arch. Oral Biol.     Publication Date:    1996 Aug-Sep
Date Detail:
Created Date:  1997-04-14     Completed Date:  1997-04-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0116711     Medline TA:  Arch Oral Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  901-4     Citation Subset:  D; IM    
Department of Anatomy and Physiology, University of Dundee, U.K.
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MeSH Terms
Carbonic Anhydrases / analysis*
Keratinocytes / enzymology
Merkel Cells / enzymology*
Middle Aged
Mouth Mucosa / cytology*,  enzymology*
Reg. No./Substance:
EC Anhydrases

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