Document Detail

An immunocytochemical comparison of the angiotensin and vasopressin hypothalamo-neurohypophysial systems in normotensive rats.
MedLine Citation:
PMID:  1805297     Owner:  NLM     Status:  MEDLINE    
In the present study we investigated the possibility that angiotensin II/III and vasopressin coexist in the hypothalamo-neurohypophysial pathway. For our experiments 8-week-old male rats not treated with colchicine were used. The anatomical orientation of the entire pathway for angiotensin and vasopressin was facilitated by examining a series of subsequent coronal, horizontal and sagittal sections. Arching fibre tracts are formed mainly by projections emanating from cell bodies in the paraventricular nucleus, the accessory magnocellular nuclei, the supraoptic nucleus and the retrochiasmatic part of the supraoptic nucleus. The majority extend as far as the median eminence and the neurohypophysis, where major terminal fields exist. However, there is a difference between the staining pattern within the suprachiasmatic nucleus and the hypophysis. The results clearly show the colocalization of angiotensin and vasopressin in neurones as well as in fibres of the hypothalamo-neurohypophysial system.
H Imboden; D Felix
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Regulatory peptides     Volume:  36     ISSN:  0167-0115     ISO Abbreviation:  Regul. Pept.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-05-01     Completed Date:  1992-05-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8100479     Medline TA:  Regul Pept     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  197-218     Citation Subset:  IM    
University of Berne, Division of Neurobiology, Switzerland.
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MeSH Terms
Angiotensin II / immunology,  isolation & purification
Angiotensin III / immunology,  isolation & purification
Angiotensins / immunology,  isolation & purification*
Blood Pressure / physiology*
Hypothalamo-Hypophyseal System / anatomy & histology,  chemistry*,  immunology
Rats, Inbred Strains
Vasopressins / immunology,  isolation & purification*
Reg. No./Substance:
0/Angiotensins; 11000-17-2/Vasopressins; 11128-99-7/Angiotensin II; 12687-51-3/Angiotensin III

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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