Document Detail

The imaging of coeliac disease and its complications.
MedLine Citation:
PMID:  17531415     Owner:  NLM     Status:  MEDLINE    
Coeliac disease is a malabsorption syndrome in which dietary gluten damages the small bowel mucosa. Gluten contains gliadin, the primary toxic component that is primarily found in wheat, barley and rye products. The initial diagnosis of coeliac disease is usually made by endoscopic biopsy of the jejunum although sometimes imaging features can suggest the diagnosis. Once a diagnosis is made, patients need to be diet compliant and monitored for potential complications. Many complications are more common when dietary compliance is poor. Complications include intussusception (usually intermittent), ulcerative jejunitis, osteomalacia, cavitating lymph node syndrome and an increased risk of malignancies such as lymphoma, adenocarcinoma and squamous cell carcinoma. Radiological evaluation is central in the evaluation of these complications. Imaging may assist both in the diagnosis and staging of complications as well as enabling radiological guided percutaneous biopsy for complications of coeliac disease such as lymphoma. As coeliac disease is a relatively common disorder, it is likely that most radiologists will encounter the disease and its potential complications. The aim of this review article is to discuss and illustrate the role of modern radiology in evaluating the many presentations of this complex disease.
O Buckley; J O Brien; E Ward; O Doody; P Govender; W C Torreggiani
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-05-24
Journal Detail:
Title:  European journal of radiology     Volume:  65     ISSN:  0720-048X     ISO Abbreviation:  Eur J Radiol     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-26     Completed Date:  2008-06-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  483-90     Citation Subset:  IM    
Adelaide and Meath Incorporating the National Children's Hospital, Dublin, Ireland.
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MeSH Terms
Barium Sulfate / diagnostic use
Celiac Disease / complications*,  radiography*
Contrast Media
Ileitis / etiology,  radiography
Intestinal Neoplasms / etiology,  radiography
Intussusception / etiology,  radiography
Lymphoma / etiology,  radiography
Tomography, X-Ray Computed
Reg. No./Substance:
0/Contrast Media; 7727-43-7/Barium Sulfate

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