| The idiopathic nephrotic syndrome. | |
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MedLine Citation:
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PMID: 10202626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The nephrotic syndrome is defined by edema, hypoalbuminemia, proteinuria, and hyperlipemia with elevated cholesterol and triglyceride concentrations in serum or plasma. It may be primary or secondary to systemic disorders. Because of its incidence--between 2.0 and 7.0 cases per 100,000 children per year--this disorder is not uncommon in a busy pediatric practice, and it forms the basis of the referrals evaluated by a pediatric nephrology service. Over the 2 years since this subject was reviewed, several articles have appeared that have provided insights into the clinical features, etiology, pathology, pathogenesis, complications, and therapy of the idiopathic primary nephrotic syndrome. Nevertheless, a remarkable feature of this condition remains that the fundamental cause and pathogenesis of the most common form of primary nephrotic syndrome, minimal lesion nephrotic syndrome of childhood, is largely unknown. Hence, a huge challenge remains for researchers in the area of pediatric nephrology. |
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Authors:
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R W Chesney |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Current opinion in pediatrics Volume: 11 ISSN: 1040-8703 ISO Abbreviation: Curr. Opin. Pediatr. Publication Date: 1999 Apr |
Date Detail:
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Created Date: 1999-06-10 Completed Date: 1999-06-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9000850 Medline TA: Curr Opin Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 158-61 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, University of Tennessee, College of Medicine, Memphis 38103, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child Humans Nephrotic Syndrome* / etiology, pathology, physiopathology, therapy |
| Grant Support | |
ID/Acronym/Agency:
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HD-31326-05/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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