Document Detail


The hypoxic profile during trekking to the Pyramid Laboratory.
MedLine Citation:
PMID:  19775212     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The oxygen saturation values reported in the high altitude literature are usually taken during a few minutes of measurement either at rest or during exercise. We aimed to investigate the daily hypoxic profile by monitoring oxygen saturation for 24 h in 8 lowlanders (4 females, ages 26 to 59) during trekking from Lukla (2850 m) to the Pyramid Laboratory (5050 m). Oxygen saturation was measured (1) daily at each altitude (sm), (2) for 24-h during ascent to 3500 m, 4200 m, and on day 1 at 5050 m (lm), and (3) during a standardized exercise (em). Results: (1) the sm and lm values were 90.9% (+/-0.5) and 86.4% (+/-1.1) at 3500 m; 85.2%(+/-1.1), and 80% (+/-1.9) at 4200 m; 83.8%(+/-1) and 77% (+/-1.7) at 5050 m (p < or = 0.05); (2) the daily time spent with oxygen saturation < or =90% was 56.5% at 3500 m, 81% at 4200 m, and 95.5% at 5050 m; (3) during exercise, oxygen saturation decreased by 10.58%, 13.43%, and 11.24% at 3500, 4200, and 5050 m, respectively. In conclusion, our data show that the level of hypoxemia during trekking at altitude is more severe than expected on the basis of a short evaluation at rest and should be taken into account.
Authors:
Luca Pomidori; Daniela Bonardi; Federica Campigotto; Valter Fasano; Alessandra Gennari; Gabriele Valli; Paolo Palange; Annalisa Cogo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  High altitude medicine & biology     Volume:  10     ISSN:  1557-8682     ISO Abbreviation:  High Alt. Med. Biol.     Publication Date:  2009  
Date Detail:
Created Date:  2009-09-24     Completed Date:  2009-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100901183     Medline TA:  High Alt Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  233-7     Citation Subset:  IM; S    
Affiliation:
Centro Studi Biomedici Applicati allo Sport Universit?? di Ferrara, Italy. pmdlcu@unife.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Altitude*
Anoxia / blood*
Female
Humans
Male
Middle Aged
Monitoring, Ambulatory*
Oximetry
Oxygen / blood*
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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