| n6/n3 hypothesis and allergies: biologically plausible, but not confirmed. | |
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MedLine Citation:
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PMID: 15337627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The dietary intake of certain fatty acids might contribute to the development of atopic diseases like allergic rhinitis and asthma. We investigated the association between the ratio of n-6 and n-3 fatty acids in serum phospholipids and hay fever or allergic sensitisation in adults. Data from a population based cross-sectional study on respiratory health including measurement of fatty acids in serum phospholipids of 740 adults between 20 and 64 years of age were analysed. We could not find any significant association between n6/n3-ratio of fatty acids in serum phospholipids and hay fever or allergic sensitisation neither in the total population nor in the sub-population stratified by sex. Since no previous study on fatty acid intake confirmed the n6/n3-ratio hypothesis and this study did not find any association between the n6/n3-ratio in serum-phospholipids and hay fever or allergic sensitization, we conclude that the n6/n3- ratio hypothesis is not confirmed although biological plausible. |
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Authors:
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I Kompauer; H Demmelmair; B Koletzko; G Bolte; J Linseisen; Joachim Heinrich |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of medical research Volume: 9 ISSN: 0949-2321 ISO Abbreviation: Eur. J. Med. Res. Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-08-31 Completed Date: 2005-09-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9517857 Medline TA: Eur J Med Res Country: Germany |
Other Details:
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Languages: eng Pagination: 378-82 Citation Subset: IM |
Affiliation:
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GSF-National Research Center for Environment and Health, Institute of Epidemiology, P. O. Box 1129, D-85758 Neuherberg, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asthma / blood Cross-Sectional Studies Dietary Fats, Unsaturated / administration & dosage, blood Fatty Acids, Omega-3 Fatty Acids, Omega-6 / blood* Fatty Acids, Unsaturated / blood* Female Humans Male Middle Aged Models, Biological* Phospholipids / blood*, chemistry* Questionnaires Respiratory Hypersensitivity / blood* Rhinitis, Allergic, Seasonal / blood Triglycerides / blood* |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats, Unsaturated; 0/Fatty Acids, Omega-3; 0/Fatty Acids, Omega-6; 0/Fatty Acids, Unsaturated; 0/Phospholipids; 0/Triglycerides; 100085-40-3/Pikasol |
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