Document Detail

The hypothalamic magnocellular neurosecretory system of the guinea pig. II. Immunohistochemical localization of neurophysin and vasopressin in the fetus.
MedLine Citation:
PMID:  1106175     Owner:  NLM     Status:  MEDLINE    
The development of the hypothalamic magnocellular neurosecretory system of the fetal guinea pig was examined by immunohistochemistry. Neurophysin was first observed in the supraoptic nucleus (SON), median eminence (ME) and posterior pituitary (PP) on day 40 of gestation. It was not regularly present in the paraventricular nucleus (PVN) until day 47. Vasopressin was first observed in the SON, ME and PP on day 45. In the median eminence immunoreactive deposits indicative of both peptides were observed in both the fibers of the hypothalamo-hypophysial tract (H-HT) in the presumptive zona interna as well as in axons projecting to the developing primary portal plexus.
A J Silverman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of anatomy     Volume:  144     ISSN:  0002-9106     ISO Abbreviation:  Am. J. Anat.     Publication Date:  1975 Dec 
Date Detail:
Created Date:  1976-02-21     Completed Date:  1976-02-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376312     Medline TA:  Am J Anat     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  445-59     Citation Subset:  IM    
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MeSH Terms
Fluorescent Antibody Technique
Guinea Pigs / embryology*
Hypothalamus / embryology*
Neurophysins / analysis*
Neurosecretory Systems / analysis,  embryology*
Paraventricular Hypothalamic Nucleus / analysis
Pituitary Gland, Posterior / analysis
Supraoptic Nucleus / analysis
Vasopressins / analysis*
Reg. No./Substance:
0/Neurophysins; 11000-17-2/Vasopressins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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