Document Detail


A hypertensive substance found in the blood of spontaneously hypertensive rats.
MedLine Citation:
PMID:  6717244     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A substance has been obtained from the blood of spontaneously hypertensive rats which produces a hypertensive elevation of the blood pressure in normotensive rats. The substance is dialyzable and is associated with the erythrocyte membrane. It appears to be relatively long-lived in its effect on arterial pressure. The erythrocyte fractions that exhibit pressor activity also stimulate the in vitro uptake of calcium by aortas obtained from normotensive animals. This suggests that the hypertensive factor or related substances may influence the calcium metabolism of vascular tissue.
Authors:
G L Wright; W D McCumbee
Related Documents :
24689594 - A compact bellows-driven diamond anvil cell for high-pressure, low-temperature magnetic...
25268094 - Effects of different antihypertensive drugs on blood pressure variability in patients w...
11743364 - Pro-erectile effect of systemic apomorphine: existence of a spinal site of action.
25273554 - Prevention of metabolic disorders with telmisartan and indapamide in a chinese populati...
7484024 - A new method of using gas exchange measurements for the noninvasive determination of ca...
12937584 - The spectral qualities of postural control are unaffected by 4 days of ankle-brace appl...
Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Life sciences     Volume:  34     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-06-14     Completed Date:  1984-06-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1521-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Calcium / metabolism
Erythrocyte Membrane / analysis,  physiology
Hypertension / blood*
Male
Muscle, Smooth, Vascular / metabolism
Rats
Rats, Inbred Strains
Grant Support
ID/Acronym/Agency:
5 RO1 HL28524-02/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in...
Next Document:  Pre-decapitation state of arousal of rats predetermines the effect of des-Tyr1-gamma-endorphin on do...