Document Detail

The hydrolysis of dolichyl palmitate by intestinal mucosa.
MedLine Citation:
PMID:  7104377     Owner:  NLM     Status:  MEDLINE    
A dolichyl palmitate esterase was found in cell-free extracts of both pancreas and intestinal mucosa. The substrate for the reaction was dolichyl palmitate that was synthesized with labeled fatty acid. The reaction was monitored by the liberation of the free fatty acid and HPLC. All polyprenol esters studied were hydrolyzed despite differences in chain length. The role of this enzyme might be to promote the absorption of dolichol from the diet.
R W Keenan; N Rice; G S Adrian
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biochimica et biophysica acta     Volume:  711     ISSN:  0006-3002     ISO Abbreviation:  Biochim. Biophys. Acta     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-10-29     Completed Date:  1982-10-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0217513     Medline TA:  Biochim Biophys Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  490-3     Citation Subset:  IM    
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MeSH Terms
Chromatography, High Pressure Liquid
Deoxycholic Acid / pharmacology
Dolichol* / analogs & derivatives*
Esterases / metabolism*
Intestinal Mucosa / enzymology*
Intestine, Small / enzymology
Palmitic Acids / metabolism*
Pancreas / enzymology
Taurocholic Acid / pharmacology
Terpenes / metabolism*
Grant Support
Reg. No./Substance:
0/Palmitic Acids; 0/Terpenes; 2067-66-5/Dolichol; 81-24-3/Taurocholic Acid; 82446-32-0/dolichyl palmitate; 83-44-3/Deoxycholic Acid; EC 3.1.-/Esterases

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