| A hydatidiform mole in a postmenopausal woman. A case report and review of the literature. | |
| | |
MedLine Citation:
|
PMID: 15338558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Gestational trophoblastic disease occurs in less than 1 per 1200 pregnancies in the United States. The spectrum of this disease ranges from benign hydatidiform mole to trophoblastic malignancy (placental-site trophoblastic tumor and choriocarcinoma). Benign gestational trophoblastic disease generally occurs in women of reproductive age and is extremely rare in postmenopausal women. To our knowledge, our case represents only the third description in the world literature of a benign complete hydatidiform mole in a woman with a history of amenorrhea greater than 1 year. We describe the case of a 61-year-old postmenopausal woman who underwent an emergent total abdominal hysterectomy due to uncontrollable vaginal bleeding associated with an increased serum beta-human chorionic gonadotropin level. The resected uterus contained an endometrial, cystic, grapelike tumor. Microscopic examination demonstrated hydropic degenerated villi with a circumferential trophoblastic cell proliferation and moderate atypia, consistent with a complete hydatidiform mole. The morphologic and immunophenotypic characteristics are presented, as well as the results of a literature review. |
| | |
Authors:
|
Monica Garcia; Rita L Romaguera; Carmen Gomez-Fernandez |
Related Documents
:
|
6945538 - Multiosseous osteosarcoma involving the mandible: metastatic or multicentric? 21062598 - Syringocystadenoma papilliferum in an unusual location beyond the head and neck region:... 10443828 - Upper aerodigestive tract liposarcoma: report on four cases and literature review. 10999698 - Ewing's sarcoma/primitive neuroectodermal tumor of the ureter: a case report and review... 19505558 - Local uses of aristolochia species and content of nephrotoxic aristolochic acid 1 and 2... 3336338 - Hepatic granulomas: a 15-year experience in the royal adelaide hospital. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: Archives of pathology & laboratory medicine Volume: 128 ISSN: 1543-2165 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 2004 Sep |
Date Detail:
|
Created Date: 2004-08-31 Completed Date: 2005-02-28 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: United States |
Other Details:
|
Languages: eng Pagination: 1039-42 Citation Subset: AIM; IM |
Affiliation:
|
Department of Pathology, University of Miami School of Medicine, Miami, Fla, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Factors Chorionic Gonadotropin / analysis Female Humans Hydatidiform Mole / chemistry, pathology* Immunohistochemistry Middle Aged Postmenopause* Pregnancy Uterine Neoplasms / chemistry, pathology* |
| Chemical | |
Reg. No./Substance:
|
0/Chorionic Gonadotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Progression of chronic myeloid leukemia to blast crisis during treatment with imatinib mesylate.
Next Document: An isolated vertebral metastasis of urachal adenocarcinoma.