Document Detail


A hybrid PDMS-Parylene subdural multi-electrode array.
MedLine Citation:
PMID:  23334754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this paper, we report on a cost effective and simple method for fabricating a flexible multi-electrode array for subdural neural recording. The electrode was fabricated using a PDMS-Parylene bilayer to combine the major advantages of both materials. Mechanical and electrical characterizations were performed to confirm functionality of a 16-site electrode array under various flexed/bent conditions. The electrode array was helically wound around a 3 mm diameter cylindrical tube and laid over a 2 cm diameter sphere while maintaining its recording capability. Experimental results showed impedance values between 300 kΩ and 600 kΩ at 1 kHz for 90 μm diameter gold recording sites. Acoustically evoked neural activity was successfully recorded from rat auditory cortex, confirming in vivo functionality.
Authors:
Manuel Ochoa; Pinghung Wei; Andrew J Wolley; Kevin J Otto; Babak Ziaie
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Biomedical microdevices     Volume:  15     ISSN:  1572-8781     ISO Abbreviation:  Biomed Microdevices     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-10     Completed Date:  2014-01-13     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  100887374     Medline TA:  Biomed Microdevices     Country:  United States    
Other Details:
Languages:  eng     Pagination:  437-43     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Dimethylpolysiloxanes / chemistry*
Electricity
Electrophysiological Processes
Mechanical Processes
Microelectrodes
Microtechnology / instrumentation*
Polymers / chemistry*
Rats
Subdural Space
Xylenes / chemistry*
Grant Support
ID/Acronym/Agency:
R21 EB005351/EB/NIBIB NIH HHS; R21-EB 005351-02/EB/NIBIB NIH HHS
Chemical
Reg. No./Substance:
0/Dimethylpolysiloxanes; 0/Polymers; 0/Xylenes; 25722-33-2/parylene; 63148-62-9/baysilon
Comments/Corrections

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