| The human respiratory nasal mucosa in nasal syphilis. A histochemical study. | |
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MedLine Citation:
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PMID: 6235704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The enzymatic changes in tertiary nasal syphilis were studied in 5 patients. The cholinesterase was increased in the subepithelium, around the glands and blood vessels, denoting parasympathetic hyperactivity. Acid phosphatase was increased in the epithelium, stromal histiocytes, around the glands and ducts, indicating increased phagocytotic activity. Alkaline phosphatase was increased in the capillary endothelium and periglandular stroma, denoting marked vascular changes. Succinic dehydrogenase, alkaline phosphatase, alpha esterase and PAS-alcian blue were diminished in the epithelium and glands, denoting diminished secretory activity, hence a diminished natural defence mechanism of the nasal mucosa. When serological tests are inconclusive, these findings become an important adjuvant to a final diagnosis. |
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Authors:
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H Toppozada; I el-Ghazzawi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 97 ISSN: 0001-6489 ISO Abbreviation: Acta Otolaryngol. Publication Date: 1984 May-Jun |
Date Detail:
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Created Date: 1984-08-28 Completed Date: 1984-08-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 419-25 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid Phosphatase
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metabolism Adult Alkaline Phosphatase / metabolism Esterases / metabolism Glycosaminoglycans / metabolism Histocytochemistry Humans Male Middle Aged Nasal Mucosa / enzymology*, pathology Succinate Dehydrogenase / metabolism Syphilis / enzymology*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Glycosaminoglycans; EC 1.3.99.1/Succinate Dehydrogenase; EC 3.1.-/Esterases; EC 3.1.3.1/Alkaline Phosphatase; EC 3.1.3.2/Acid Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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