Document Detail


The human pyramidal syndrome Redux.
MedLine Citation:
PMID:  17712266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Experimental studies in nonhuman primates have questioned the selectivity of pyramidal tract damage in giving rise to the classical pyramidal syndrome in humans, characterized by permanent spastic hemiplegia (PSH). According to this view, concomitant injury of extrapyramidal pathways is necessary for the development of both hemiplegia and spasticity. In this study we used conventional magnetic resonance imaging and diffusion tensor imaging tractography to characterize the anatomical correlates of PSH in a patient with a rare and discrete unilateral lesion of the medullary pyramid. Our findings support the hypothesis that damage confined to the medullary pyramid/pyramidal tract is sufficient to produce PSH. In contrast to nonhuman primates, the human 'pyramidal' and 'pyramid' syndromes are equivalent clinico-anatomic concepts.
Authors:
Fernanda Tovar-Moll; Jorge Moll; Ivanei Edson Bramati; Andrea Silveira de Souza; Pedro Angelo Andreiuolo; Ricardo de Oliveira-Souza
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroreport     Volume:  18     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-22     Completed Date:  2007-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  England    
Other Details:
Languages:  eng     Pagination:  1417-21     Citation Subset:  IM    
Affiliation:
Department of Anatomy, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Brazil. tovarmollf@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Diffusion Magnetic Resonance Imaging / methods
Female
Hemiplegia / pathology*,  physiopathology
Humans
Imaging, Three-Dimensional
Male
Middle Aged
Neuropsychological Tests
Pyramidal Tracts / pathology*,  physiopathology
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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