Document Detail


The human homolog of the Moloney leukemia virus integration 2 locus (MLV12) maps to band p14 of chromosome 5.
MedLine Citation:
PMID:  2793187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Moloney leukemia virus integration 2 (MLV12) locus represents a common region for proviral integration and a putative oncogene involved in the induction of thymic lymphomas in rodents. The human homolog of the MLV12 locus has been cloned and studies have been initiated to determine its possible role in the induction and progression of human neoplasms. In this study we used a panel of human X rodent somatic cell hybrids and in situ hybridization to metaphase chromosomes to map MLV12 to the short arm of the human chromosome 5, band p14.
Authors:
N P Anagnou; A Economou-Pachnis; S J O'Brien; W S Modi; A W Nienhuis; P N Tsichlis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Genomics     Volume:  5     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1989-11-09     Completed Date:  1989-11-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  354-8     Citation Subset:  IM    
Affiliation:
Department of Basic Sciences, University of Crete School of Medicine, Greece.
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MeSH Terms
Descriptor/Qualifier:
Animals
Attachment Sites, Microbiological*
Blotting, Southern
Chromosome Mapping
Chromosomes, Human, Pair 5*
Cloning, Molecular
Humans
Hybrid Cells
Lysogeny*
Mice
Moloney murine leukemia virus / genetics*
Oncogenes*
Grant Support
ID/Acronym/Agency:
CA-06927/CA/NCI NIH HHS; CA-38047/CA/NCI NIH HHS; RR-05539/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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