Document Detail


The human anterior cruciate ligament: histological and ultrastructural observations.
MedLine Citation:
PMID:  1487443     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In transverse and longitudinal paraffin-embedded sections, the human anterior cruciate ligament (ACL) is made up of wavy bundles of collagen fibres arrayed in various directions, the majority around the axis of the ligament with a few running parallel to it. The fascicles making up the larger bundles are also characterised by this undulating appearance. In thin sections 2 types of collagen fibrils are observed: small (with a single diameter peak at 45 nm) and large (3 peaks at 35, 50 and 75 nm respectively), organised into distinct areas made up of either large or small bundles of fibrils. The numerous fibroblasts that are present appear elongated in the direction of the bundles with branches and short cytoplasmic processes. The elastic system is made up of both elastic and oxytalan fibres. The varied orientation of the bundles in the ACL, the complex ultrastructural organisation and the abundant elastic system make it very different from other ligaments and tendons, providing a structure able to withstand the multiaxial stresses and varying tensile strains imposed upon it.
Authors:
R Strocchi; V de Pasquale; P Gubellini; A Facchini; M Marcacci; R Buda; S Zaffagnini; A Ruggeri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of anatomy     Volume:  180 ( Pt 3)     ISSN:  0021-8782     ISO Abbreviation:  J. Anat.     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1993-02-22     Completed Date:  1993-02-22     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0137162     Medline TA:  J Anat     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  515-9     Citation Subset:  IM    
Affiliation:
Institute of Human Anatomy, Bologna University, Italy.
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MeSH Terms
Descriptor/Qualifier:
Anterior Cruciate Ligament / anatomy & histology*,  ultrastructure
Collagen / analysis,  ultrastructure
Humans
Chemical
Reg. No./Substance:
9007-34-5/Collagen
Comments/Corrections
Comment In:
J Anat. 1992 Dec;181 ( Pt 3):521-2   [PMID:  1304592 ]

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