Document Detail


The homeostatic rôle of bronchoconstriction.
MedLine Citation:
PMID:  11287841     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article argues in favour of the hypothesis that the homeostatic rôles of bronchoconstriction are to retract the airway tree during expiration, and to assist in the expulsion of mucus from peripheral airways by increasing the velocity of outgoing air. In asthma, this function may be dangerously exaggerated because of the presence of unusually viscous airway secretions and the remodelling of airway walls.
Authors:
D I Blyth
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  68     ISSN:  0025-7931     ISO Abbreviation:  Respiration     Publication Date:  2001  
Date Detail:
Created Date:  2001-04-05     Completed Date:  2001-07-12     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  217-23     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Affiliation:
Respiratory Unit, Glaxo Wellcome Research and Development, Stevenage, UK. dib4985@glaxowellcome.co.uk
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MeSH Terms
Descriptor/Qualifier:
Asthma / physiopathology*
Bronchoconstriction / physiology*
Homeostasis
Humans
Mucociliary Clearance / physiology*
Mucus / secretion
Respiratory Muscles / physiology*
Viscosity
Comments/Corrections
Comment In:
Respiration. 2001;68(2):133   [PMID:  11287825 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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