| The history of progressive muscular atrophy: syndrome or disease? | |
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MedLine Citation:
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PMID: 18299524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Since its first description more than a century ago, there has been much debate about the diagnostic entity progressive muscular atrophy (PMA). Initially, PMA included all forms of progressive amyotrophy. With the identification of several myogenic and neurogenic diseases and the recognition of amyotrophic lateral sclerosis (ALS), PMA was deemed to disappear as a nosologic entity at the end of the 19th century. In the last century, various other lower motor neuron syndromes were distinguished which may previously have been designated as cases of PMA. In contrast, several observations provided evidence that PMA can be linked both clinically and pathologically to ALS. Therefore, PMA should be considered as a syndromal subtype within a clinical spectrum of motor neuron diseases. |
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Authors:
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Jeldican Visser; J M B Vianney de Jong; Marianne de Visser |
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Publication Detail:
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Type: Historical Article; Journal Article |
Journal Detail:
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Title: Neurology Volume: 70 ISSN: 1526-632X ISO Abbreviation: Neurology Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-26 Completed Date: 2008-03-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: United States |
Other Details:
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Languages: eng Pagination: 723-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands. j.visser@amc.uva.nl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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History, 19th Century History, 20th Century History, 21st Century Humans Motor Neuron Disease / history* Muscular Atrophy / history* Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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