| A historical perspective on the discovery of adenyl purines. | |
| | |
MedLine Citation:
|
PMID: 11232205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In 1929, Drury and Szent-Gyorgyi described the effects of a simple extract of heart muscle and other tissues on the mammalian heart. This extract was identified as adenylic acid and found to have profound effects on the cardiovascular system. The discovery and identification of adenyl purines and their effects on the cardiovascular system has now extended to other biological functions such as neurotransmission, neuromodulation, and endocrine/exocrine secretory functions and beyond. This review examines the history of the discovery and identification of the many roles played by adenyl purines in regulation of physiological homeostasis. |
| | |
Authors:
|
D J Cheek; J M McHugh; J Blood-Siegfried; J F McFetridge; B S Turner |
Related Documents
:
|
16470755 - Determination of acid-base dissociation constants of amino- and guanidinopurine nucleot... 22806635 - Bacterial community dynamics, lactic acid bacteria species diversity and metabolite kin... 1971185 - Mycophenolic acid and thiazole adenine dinucleotide inhibition of tritrichomonas foetus... 2033055 - Biosynthesis of nucleotides, flavins, and deazaflavins in methanobacterium thermoautotr... 11055725 - Negative ion mass spectrometry of sialylated carbohydrates: discrimination of n-acetyln... 7191805 - A quantitative study of free amino acids in eccrine sweat collected from the forearms o... |
Publication Detail:
|
Type: Historical Article; Journal Article |
Journal Detail:
|
Title: Biological research for nursing Volume: 1 ISSN: 1099-8004 ISO Abbreviation: Biol Res Nurs Publication Date: 2000 Apr |
Date Detail:
|
Created Date: 2001-03-05 Completed Date: 2001-03-22 Revised Date: 2006-10-13 |
Medline Journal Info:
|
Nlm Unique ID: 9815758 Medline TA: Biol Res Nurs Country: United States |
Other Details:
|
Languages: eng Pagination: 265-75 Citation Subset: IM; N |
Affiliation:
|
School of Nursing Biological Research Laboratory, Duke University School of Nursing, Durham, NC, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenine Nucleotides
/
history* Animals Cardiovascular System History, 20th Century Homeostasis Humans Myocardium* Neurotransmitter Agents / history Physiology / history* Signal Transduction |
| Chemical | |
Reg. No./Substance:
|
0/Adenine Nucleotides; 0/Neurotransmitter Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A comparison of hemodynamic changes during the transition from mechanical ventilation to T-piece, pr...
Next Document: Behavioral effects of transient cerebral ischemia.