Document Detail

A historical account of the "wet lung of trauma" and the introduction of intermittent positive-pressure oxygen therapy in world war II.
MedLine Citation:
PMID:  7011232     Owner:  NLM     Status:  MEDLINE    
During World War II, my associates and I observed for the first time in medical history that casualties with severe brain, thoracic, abdominal, and extremity trauma, who had persistent "wet" respiration (wet lung of trauma), were most difficult to resuscitate, withstood operation poorly, and had the highest mortality. The etiology appeared to be ineffectual cough and persistent bronchopulmonary fluid from hemorrhage, pulmonary transudates resulting from anoxia, airway obstruction, and unknown causes secondary to trauma, some of which have been discovered since then. Our treatment consisted of assisting cough, transnasal tracheobronchial aspiration and oxygenation, bronchoscopy, and tracheostomy. To treat the advanced form, pulmonary edema, I devised an effectual hand-operated intermittent positive-pressure oxygen machine, which has been supplanted by elegant automatic volume- and pressure-regulated devices. Through the use of the intermittent positive-pressure breathing machines, most hospitals have developed thriving departments of respiratory therapy. Better physiological monitoring and use of intermittent mandatory ventilation and positive end-expiratory pressure have improved the care, but our basic principles of treatment are still the standards of respiratory therapy.
L A Brewer
Publication Detail:
Type:  Biography; Historical Article; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  31     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-05-21     Completed Date:  1981-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  386-93     Citation Subset:  AIM; IM; Q    
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MeSH Terms
History, 20th Century
Intermittent Positive-Pressure Ventilation / history*,  instrumentation
Middle Aged
Military Medicine / history
Oxygen / therapeutic use
Positive-Pressure Respiration / history*
Respiratory Distress Syndrome, Adult / etiology,  history*,  therapy
Thoracic Injuries / complications*
United States
Reg. No./Substance:
Personal Name Subject
Personal Name Subject:
L A Brewer; E D Churchill

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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