| The histopathology of the spleen from a patient with lepromatous leprosy. | |
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MedLine Citation:
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PMID: 6969229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The histopathology of the spleen from a young man with diffuse non-nodular lepromatous leprosy is reported. As judged by this case, other case reports, and necropsy series, involvement of the spleen in lepromatous leprosy is characterized by aggregations of large vacuolated histiocytes, containing individual bacilli and globi, in both the red and white pulp. In the white pulp the histiocytes localize about the arterioles. Findings in the present case, which may represent a comparatively early change, include numerous, small germinal centers containing nonaggregated large, vacuolated histiocytes with intracellular bacilli. |
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Authors:
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T H Rea; L Bevans; C R Taylor |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association Volume: 48 ISSN: 0148-916X ISO Abbreviation: Int. J. Lepr. Other Mycobact. Dis. Publication Date: 1980 Sep |
Date Detail:
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Created Date: 1981-02-19 Completed Date: 1981-02-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8505819 Medline TA: Int J Lepr Other Mycobact Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 285-90 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Histiocytes / pathology Humans Leprosy / immunology, pathology* Male Spleen / pathology* T-Lymphocytes / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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