| The histopathologic effects of balloon dacryoplasty on the rabbit nasolacrimal duct. | |
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MedLine Citation:
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PMID: 16935233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To examine the histopathologic effects of balloon dacryoplasty on the nasolacrimal duct of the rabbit. METHODS: Sixteen nasolacrimal ducts of 8 infant white New Zealand rabbits were divided into 3 treatment groups: a control group, a 2 mm balloon dilation group, and a 3 mm balloon dilation group. The LacriCath balloon catheter (Quest, Medical, Allen, TX) was used for nasolacrimal duct dilation according to the manufacturer's recommended human protocol. The rabbits were euthanized at 1, 3, and 7 days after treatment and the nasolacrimal ducts were harvested for histological examination. RESULTS: There were no significant differences between treatment groups in the number of neutrophils in the lumen, epithelium, and stroma of the duct; the number of monocytes in the stroma of the duct; or in the number of red blood cells in the stroma of the duct. No differences were found in overall cellularity of any type in the nasolacrimal ducts of treated and untreated rabbits. Finally, no histopathologic signs of crush injury were evident. CONCLUSION: Balloon dacryoplasty does not induce significant inflammation or crush injury in the nasolacrimal duct of a rabbit model. |
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Authors:
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Scott M Goldstein; James A Katowitz; Nasreen A Syed |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus Volume: 10 ISSN: 1091-8531 ISO Abbreviation: J AAPOS Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-08-28 Completed Date: 2006-09-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9710011 Medline TA: J AAPOS Country: United States |
Other Details:
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Languages: eng Pagination: 333-5 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, Children's Hospital of Philadelphia and Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. ScottyGMD@Comcast.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Balloon Dilatation / methods* Dacryocystorhinostomy / methods* Lacrimal Duct Obstruction / therapy Nasolacrimal Duct / pathology* Rabbits |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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