Document Detail


A histomorphometric study of cellular layers after hemiepiphyseal stapling on the physeal plate in rabbits.
MedLine Citation:
PMID:  23117869     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Epiphyseal stapling has been widely used to correct angular deformity. The mechanism, however, has not been well determined. To determine the effect of temporary hemiepiphyseal stapling on the cellular layers of the physis, a histomorphometric study was performed using immature rabbits. METHODS: Distal lateral epiphyseal stapling of the right femur was performed on 6-week-old New Zealand white rabbits. Thirty rabbits were randomly assigned to five groups, and six rabbits in each group were analyzed weekly for up to 5 weeks. RESULTS: The distal femur was deformed into the valgus, and the anatomical lateral distal femoral angle decreased with the passage of time. In the sequential histomorphometry of the operated physeal plate, the area ratio of each layer, compared to the control side, decreased every week. The total area of the physeal plate had decreased up to 60 % at the 5th week compared to the area of the 1st week, and the area of the proliferative layer decreased by the greatest amount among the three layers. CONCLUSIONS: Our findings suggest that the proliferation of chondrocytes seemed to be more suppressed by the compression of the stapling, thereby slowing the growth rate, although hypertrophy of the chondrocytes was also suppressed.
Authors:
Su-Min Son; Il-Hyung Park; Chang-Wug Oh; Hyun-Joo Lee; Byung-Chul Park; Je-Yong Choi
Related Documents :
23846869 - Hydrogel dressings for healing diabetic foot ulcers.
19181469 - Diffusion-weighted imaging for the follow-up of patients after matrix-associated autolo...
24471979 - Topical pdt following excisional wounding of human skin increases production of tgf-β3...
19233419 - Ureteropelvic junction obstruction secondary to crossing vessels-to transpose or not? t...
21519749 - Systemic inflammation and carotid diameter in obese patients: pilot comparative study w...
17161089 - Immediate laparoscopic cholecystectomy for acute cholecystitis: no need to wait.
16303399 - The parameter stability of a high dk rigid lens material.
465959 - Experience wiht vasovasostomy: operative technique and results.
3799219 - Tissue damage at computed tomography following resolution of intracerebral hematomas.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-2
Journal Detail:
Title:  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association     Volume:  -     ISSN:  1436-2023     ISO Abbreviation:  J Orthop Sci     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9604934     Medline TA:  J Orthop Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Good-morning Hospital, 972, Dal-dong, Nam-gu, Ulsan, 680-804, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Imaging multiple sclerosis and other neurodegenerative diseases.
Next Document:  Fabricating metamaterials using the fiber drawing method.