Document Detail

The histological spectrum of acquired nevi. An analysis of the intraepidermal melanocytic proliferation in common and dysplastic nevi.
MedLine Citation:
PMID:  7984520     Owner:  NLM     Status:  MEDLINE    
The histological intraepidermal characteristics considered to be specific to dysplastic nevi (radial extension, lentiginous and disordered nest proliferations, cytological atypia or dyskaryosis) were investigated in a series of 114 acquired nevi showing various clinical appearances in an attempt to establish whether dysplastic nevi can be considered a homogeneous class of lesions, clearly distinct from common nevi. On the basis of the distribution of investigated architectural features, found singly or variously associated, the examined lesions were divided into 5 groups, showing an increasing incidence of dyskaryosis. Results suggest that acquired nevi, rather than two distinct classes (common and dysplastic nevi), form a histological spectrum of lesions, within which the border between lesions implying and not implying an increased melanoma risk cannot be objectively fixed.
C Urso; R Bondi
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pathology, research and practice     Volume:  190     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1995-01-05     Completed Date:  1995-01-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  609-14     Citation Subset:  IM    
Institute of Anatomic Pathology, University of Firenze, Italy.
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MeSH Terms
Cell Division
Dysplastic Nevus Syndrome / pathology*
Epidermis / pathology
Melanocytes / pathology
Nevus / pathology*
Skin Neoplasms / pathology*

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