| The histologic effect of intraventricular injection of metrizamide. | |
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MedLine Citation:
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PMID: 7055452 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient with sudden apoplexy and coma was found to have hydrocephalus on computed tomographic scan, and metrizamide was instilled into the ventricles. Subsequent autopsy disclosed a brainstem infarct secondary to a primary dissecting aneurysm of the basilar artery, and a histologic picture of encephalitis in the walls of the lateral and third ventricles. Metrizamide may cause pathologic changes that must be recognized for the correct interpretation by the pathologist of tissue sections previously exposed to metrizamide. In the present case, the changes were seen 11 days after exposure of the tissue to metrizamide, consonant with the time course of similar changes observed in animals. The localization of the cellular infiltrates to the Virchow-Robin spaces corroborates evidence from the literature that metrizamide enters brain parenchyma via these spaces. |
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Authors:
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R N Auer; A J Fox; J C Kaufmann |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of neurology Volume: 39 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1982 Jan |
Date Detail:
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Created Date: 1982-03-22 Completed Date: 1982-03-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 60-1 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arachnoiditis / chemically induced, pathology Brain Diseases / etiology, pathology* Female Humans Injections, Intraventricular Metrizamide / administration & dosage, adverse effects* |
| Chemical | |
Reg. No./Substance:
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31112-62-6/Metrizamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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