| The histamine-induced skin reaction in schizophrenic and normal subjects. | |
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MedLine Citation:
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PMID: 7054159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most published data on histamine skin tests on schizophrenic patients show them to be insensitive relative to normals or other psychotic patients. However, experimental conditions have varied and in most cases only a single dose of histamine was used. We have compared 13 volunteer controls and 16 paranoid schizophrenics; each subject was injected intradermally with histamine, 10, 20, and 50 microgram, doses predetermined in volunteers to give a dose-response curve. Wheal and flare were measured at 10 and 20 minutes, intervals near the time of maximum flare. We found no statistically significant differences between normal controls and schizophrenic patients. |
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Authors:
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R W Schayer; A Pilc; A Zaborwski; W Kazimierczak; C Maslinski |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of clinical psychiatry Volume: 43 ISSN: 0160-6689 ISO Abbreviation: J Clin Psychiatry Publication Date: 1982 Jan |
Date Detail:
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Created Date: 1982-03-26 Completed Date: 1982-03-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7801243 Medline TA: J Clin Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 7-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Histamine / analogs & derivatives*, immunology Humans Intradermal Tests Middle Aged Receptors, Histamine H2 / immunology Schizophrenia / immunology* Schizophrenia, Paranoid / immunology |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Histamine H2; 51-45-6/Histamine; 51-74-1/histamine phosphate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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